metastasize

verb

me·​tas·​ta·​size mə-ˈta-stə-ˌsīz How to pronounce metastasize (audio)
metastasized; metastasizing

intransitive verb

: to spread or grow by or as if by metastasis
died of lung cancer which had metastasized throughout his bodyG. P. Elliott

Examples of metastasize in a Sentence

Recent Examples on the Web Mom and son’s royal ambitions metastasize from there, leading to family backbiting, a beheading or two, murder, death and more plots. Randy Myers, The Mercury News, 4 Apr. 2024 But as Yoong’s experience grimly shows, the Golden Triangle’s criminal reboot has metastasized beyond narcotics. TIME, 21 Mar. 2024 For others, the anger of those pandemic days has metastasized into a deeper lack of faith in politics. Reid J. Epstein, New York Times, 24 Mar. 2024 My sister was diagnosed with non-small cell lung cancer that metastasized to her bones. Letter Writers, Twin Cities, 11 Feb. 2024 She was initially diagnosed with Stage III HER2+ PR/ER IDC breast cancer, which progressed to Stage 4 after metastasizing to her lungs. Sandra Rose Salathe, Peoplemag, 11 Oct. 2023 Just like humans, our canine friends can also develop soft tissue sarcomas underneath their skin, which can metastasize and spread with fatal consequences. Juergen Eckhardt, Forbes, 22 Feb. 2024 In the fall of 2020, Robert Sachs was prescribed a medication to treat prostate cancer that had metastasized into some of his bones. Ed Silverman, STAT, 22 Jan. 2024 The strikes represent a significant escalation of U.S. involvement in the Middle East amid Israel’s war in Gaza − and perhaps the most dangerous escalation of a conflict that threatens to metastasize across the region. Tom Vanden Brook, USA TODAY, 13 Jan. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'metastasize.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of metastasize was in 1907

Dictionary Entries Near metastasize

Cite this Entry

“Metastasize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metastasize. Accessed 16 Apr. 2024.

Kids Definition

metastasize

verb
me·​tas·​ta·​size mə-ˈtas-tə-ˌsīz How to pronounce metastasize (audio)
: to spread or grow by or as if by metastasis

Medical Definition

metastasize

intransitive verb
me·​tas·​ta·​size
variants also British metastasise
metastasized also British metastasised; metastasizing also British metastasising
: to spread by metastasis
… all ten were primary brain cancers; that is, they had originated in the brain, and not metastasized there from elsewhere in the body.Paul Brodeur, The New Yorker
metastasization noun
also British metastasisation
Last Updated: - Updated example sentences
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